Multiple Myeloma

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Thank you Dr. Michael Ayoub for an excellent presentation on Multiple Myeloma

Teaching Points:

  • Multiple myeloma is a proliferation of a plasma cell population
  • Dx with bone marrow biopsy or plasmacytoma AND evidence of end-organ damage
  • End organ damage: hyeprcalcemia, renal insufficiency, anemia, bone lesions (CRAB)
  • Hypervisosity syndrome
    • Occurs in 2-6% of multiple myeloma
    • IgM more frequently involved than IgG or IgA
    • Treatment is plasmapheresis

Power Point: Morning Report 9-26-16

Further Reading: 
Recent advances in understanding multiple myeloma