Monthly Archives: August 2016

Tolosa Hunt Syndrome

Cavernous-sinus

Teaching Points:

Definition: Episodic orbital pain associated with paralysis of one or more of the CN III, IV, VI due to granulomatous inflammation of the cavernous sinus

Presents with episodic painful ophthalmoplegia, CNIII, IV, VI Palsy leading to diplopia, usually unilateral, headache often precedes paresis

Etiology – inflammation unknown etiology

Treatment – glucocorticoids

Morning Report 8.23.16 – Tolosa Hunt

Drug reaction with eosinophilia and systemic symptoms (DRESS)

OLYMPUS DIGITAL CAMERA

Teaching Points

  • Potentially life-threatening, drug-induced hypersensitivity reaction
  • Presents with fever, malaise, skin eruption, hematologic abnormalities (eosinophilia, atypical lymphocytosis), lymphadenopathy, and internal organ involvement (liver, kidney, lung)
  • Management is withdrawal of offending drug, topical or oral/IV glucocorticoids (if severe disease)

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