{"id":675,"date":"2015-11-23T18:37:22","date_gmt":"2015-11-24T02:37:22","guid":{"rendered":"http:\/\/www.oliveviewim.org\/blog\/?p=675"},"modified":"2015-11-23T18:37:22","modified_gmt":"2015-11-24T02:37:22","slug":"morning-report-catastrophic-antiphospholipid-syndrome-aka-caps","status":"publish","type":"post","link":"https:\/\/www.uclaoliveview.org\/medicine\/blog\/?p=675","title":{"rendered":"Morning Report: Catastrophic Antiphospholipid Syndrome &#8220;aka &#8220;CAPS&#8221;"},"content":{"rendered":"<p><a href=\"http:\/\/www.oliveviewim.org\/blog\/wp-content\/uploads\/2015\/11\/aps.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-large wp-image-676\" src=\"http:\/\/www.oliveviewim.org\/blog\/wp-content\/uploads\/2015\/11\/aps-600x389.jpg\" alt=\"aps\" width=\"600\" height=\"389\" \/><\/a><\/p>\n<p>Thank you Dr. Sarkisyan for an excellent case of CAPS on 11\/20\/15!<\/p>\n<p><strong><span style=\"text-decoration: underline;\">Teaching Points:<\/span><\/strong><\/p>\n<ul>\n<li><strong>CAPS:<\/strong> The most severe form of APS, an acute biologic process that leads to occlusion of vessels of multiple organs.\n<ul>\n<li>Clotting gone wild!<\/li>\n<li>MUST NOT MISS Diagnosis: <span style=\"text-decoration: underline;\">High mortality rate (30-50%)<\/span><\/li>\n<\/ul>\n<\/li>\n<li><strong>Diagnosis<\/strong> requires acute (&lt;1 week) onsets of symptoms, 3 or more organ involvement, APL antibodies, and biopsy confirmation of small vessel occlusion<\/li>\n<li>Infections are most common precipitating factors<\/li>\n<li>Think about this dx in any patient p\/w anemia and thrombocytopenia (MAHA) with evidence of end organ dysfunction (ie. Chest pain, SOB, AKI, HTN, Stroke, DVT\/PE, etc)<\/li>\n<li><strong>Treatment:<\/strong> Anticoagulation, High-dose glucocorticoids, Plasma exchange<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Thank you Dr. Sarkisyan for an excellent case of CAPS on 11\/20\/15! Teaching Points: CAPS: The most severe form of APS, an acute biologic process that leads to occlusion of vessels of multiple organs. Clotting gone wild! MUST NOT MISS Diagnosis: High mortality rate (30-50%) Diagnosis requires acute (&lt;1 week) onsets of symptoms, 3 or [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[4,1],"tags":[],"class_list":["post-675","post","type-post","status-publish","format-standard","hentry","category-inpatient-report","category-uncategorized"],"_links":{"self":[{"href":"https:\/\/www.uclaoliveview.org\/medicine\/blog\/index.php?rest_route=\/wp\/v2\/posts\/675","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.uclaoliveview.org\/medicine\/blog\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.uclaoliveview.org\/medicine\/blog\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.uclaoliveview.org\/medicine\/blog\/index.php?rest_route=\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.uclaoliveview.org\/medicine\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=675"}],"version-history":[{"count":0,"href":"https:\/\/www.uclaoliveview.org\/medicine\/blog\/index.php?rest_route=\/wp\/v2\/posts\/675\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.uclaoliveview.org\/medicine\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=675"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.uclaoliveview.org\/medicine\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=675"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.uclaoliveview.org\/medicine\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=675"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}