{"id":355,"date":"2015-08-07T18:03:10","date_gmt":"2015-08-08T01:03:10","guid":{"rendered":"http:\/\/www.oliveviewim.org\/blog\/?p=355"},"modified":"2015-08-07T18:03:10","modified_gmt":"2015-08-08T01:03:10","slug":"am-report-anaplastic-thyroid-carcinoma","status":"publish","type":"post","link":"https:\/\/www.uclaoliveview.org\/medicine\/blog\/?p=355","title":{"rendered":"AM Report: Anaplastic thyroid carcinoma"},"content":{"rendered":"<p><span style=\"color: #000000;\"><a href=\"http:\/\/www.oliveviewim.org\/blog\/wp-content\/uploads\/2015\/08\/ijinvasion.png\"><span style=\"color: #000000;\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-large wp-image-357\" src=\"http:\/\/www.oliveviewim.org\/blog\/wp-content\/uploads\/2015\/08\/ijinvasion-600x191.png\" alt=\"ijinvasion\" width=\"600\" height=\"191\" \/><\/span><\/a><\/span><\/p>\n<address style=\"text-align: center;\"><em><span style=\"color: #000000;\">Anaplastic thyroid carcinoma invading into internal jugular vein. From Takashima, et al. (PMID:\u00a02108546)<\/span><\/em><\/address>\n<p><span style=\"color: #000000;\">Thanks to Dr. Hahr for a great morning report on an unfortunate case of anaplastic thyroid carcinoma, a rare disease with very poor prognosis.<\/span><\/p>\n<p><span style=\"text-decoration: underline;\"><strong><span style=\"color: #000000;\"><em>Learning points from today&#8217;s case:<\/em><\/span><\/strong><\/span><\/p>\n<ul>\n<li><span style=\"color: #000000;\"><strong>Symptoms:<\/strong> When evaluating neck masses, make sure to screen for symptoms of compression: <strong><span style=\"text-decoration: underline;\">D<\/span><\/strong>ysphonia, <strong><span style=\"text-decoration: underline;\">D<\/span><\/strong>ysphagia, <strong><span style=\"text-decoration: underline;\">D<\/span><\/strong>yspnea.<\/span><\/li>\n<li><span style=\"color: #000000;\"><strong>Physical exam:<\/strong> Thyroid nodules in the setting of vocal cord paralysis (LR 18), cervical lymphadenopathy (LR 8), or fixation\u00a0to nearby structures (LR 8) are highly suspicious for carcinoma.\u00a0<\/span><\/li>\n<li><span style=\"color: #000000;\"><strong>Diagnostics<\/strong>: FNA is an acceptable initial approach to obtain head and neck mass tissue due to availability and\u00a0\u00a0lower morbidity. Studies have shown sensitivity &gt;90% for malignancy using this approach (PMID: <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed?term=11568593\"><span style=\"color: #000000;\">11568593<\/span><\/a>,\u00a0<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/24350168\"><span style=\"color: #000000;\">24350168<\/span><\/a>).\u00a0\u00a0 However, LN excisional biopsy is still preferred for LN architecture when feasible and suspicious for lymphoma, and core biopsy may have higher diagnostic yield (PMID:\u00a0<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/22127851\"><span style=\"color: #000000;\">22127851<\/span><\/a>).<br \/>\n<\/span><\/li>\n<li><span style=\"color: #000000;\"><strong>20-30%<\/strong> of patients with anaplastic thyroid carcinoma have coexisting differentiated thyroid carcinoma.<\/span><\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Anaplastic thyroid carcinoma invading into internal jugular vein. From Takashima, et al. (PMID:\u00a02108546) Thanks to Dr. Hahr for a great morning report on an unfortunate case of anaplastic thyroid carcinoma, a rare disease with very poor prognosis. Learning points from today&#8217;s case: Symptoms: When evaluating neck masses, make sure to screen for symptoms of compression: [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[4,1],"tags":[],"class_list":["post-355","post","type-post","status-publish","format-standard","hentry","category-inpatient-report","category-uncategorized"],"_links":{"self":[{"href":"https:\/\/www.uclaoliveview.org\/medicine\/blog\/index.php?rest_route=\/wp\/v2\/posts\/355","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.uclaoliveview.org\/medicine\/blog\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.uclaoliveview.org\/medicine\/blog\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.uclaoliveview.org\/medicine\/blog\/index.php?rest_route=\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.uclaoliveview.org\/medicine\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=355"}],"version-history":[{"count":0,"href":"https:\/\/www.uclaoliveview.org\/medicine\/blog\/index.php?rest_route=\/wp\/v2\/posts\/355\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.uclaoliveview.org\/medicine\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=355"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.uclaoliveview.org\/medicine\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=355"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.uclaoliveview.org\/medicine\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=355"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}